Recently, antihyperglycemic, antioxidant, anti-inflammatory, and lipid-lowering potential of two fractions (2.5% and 5%) of P. marsupium extract (PME) was evaluated in streptozotocin (STZ)-induced diabetic rats.
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In a study by Central Drug Research Institute, Lucknow, India, different extracts of heart wood of P. marsupium were tested for antidiabetic efficacy in streptozotocin (STZ)-induced diabetic rats.
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Various phenolic C-glycosides isolated from P. marsupium exhibited moderate-to-excellent in vivo anti-hyperglycemic activity ranging from 19.9–34.9% in STZ-induced diabetic rats when administered at a dose of 25 mg/kg.
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In a study carried out at All India Institute of Medical Sciences (AIIMS), New Delhi, India, effect of aqueous extract of P. marsupium on fructose-induced hyperglycaemia, hyperinsulinaemia and hypertriglyceridaemia was evaluated.
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Aqueous extract of P. marsupium heartwood was evaluated for hypoglycemic activity on alloxan-induced diabetic rats in both acute and subacute
tests. Results showed that the extract produced statistically significant hypoglycemic effects at an oral dose of 250 mg/kg.
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